Bernát Iván: Ozaena. A manifestation of iron deficiency (Budapest, 1965)

OZAENA A MANIFESTATION OF IRON DEFICIENCY by IVAN BERNÁT On the basis of a series of clinical examinations and animal experi­ments the author proves that ozaena, the pathogenesis of which has not been clarified as yet, is not a local disease, but one affecting the whole organism and showing symptoms of iron deficiency. Haematological and biochemical tests support this theory. The author succeeded in producing the cranial shape and pathological and histo­logical alterations characteristic of ozaena by inducing iron deficiency in animals. Subsequent therapeutic experiments have also proved that ozaena reacts well to iron prepara­tions, and iron therapy yielded excellent results in the overwhelm­ing majority of cases. The nature of neuroendocrine-functional dis­turbances in ozaena are dealt with in detail, as well as the origin of ossification disturbances; the causes of the specific manifestations of this disease are also discussed. AKADÉMIAI KIADÓ BUDAPEST

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