Hypothalamic control of the anterior pituitary. An experimental-morphological study (Budapest, 1968)

J. SZENTÁGOTHAI, В. FLERKÓ, В. MESS and В. HALÁSZ HYPOTHALAMIC CONTROL OF THE ANTERIOR PITUITARY The third edition of this Monograph — after a first edition in English in 1963 and a second edition with only minor changes in Russian in 1965 — now ap­pears again in English with considerable revisions, including several entirely new chapters and some others completely re-written. The Monograph gives a de­tailed anatomical and histological anal­ysis of the hypothalamo-hypophyseal complex, with due regard to the interests of the experimenter (stereotaxic atlas, Golgi architecture, synaptology, hypo­thalamic pathways, blood circulation and innervation of the pituitary gland). An extensive experimental material con­cerning hypothalamic control of thyro­­trophic, adrenocorticotrophic, gonado­trophic and — newly added in this edi­tion — of somatotrophic functions is pre­sented. A new Chapter (III) deals with the specific — and to some extent autonomous — role of a certain limited region of the hypothalamus (hypophysio­­trophic area) in the maintenance of structure and functions of the anterior pituitary gland. The Monograph is of specific interest for the experimental and clinical endocrinol­ogist. Owing to the daring and provoca­tive raising of new concepts, such as direct internal feedback mechanisms and purely nervous feedback loops involved, and several rather unusual histological and experimental modes of approach, the volume is a stimulating reading for everybody interested in experimental medicine and biology. AKADÉMIAI KIADÓ BUDAPEST

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