Winterfeldt, E.: Approaches to camptothecin - Recent developments in the chemistry of natural carbon compounds 6. (Budapest, 1975)

RECENT DEVELOPMENTS IN THE CHEMISTRY OF NATURAL CARBON COMPOUNDS Volume 6 The present book in this succes­sion of volumes dealing with natural organic compounds con­tains three reviews, written by distinguished authors who are themselves active workers in the fields concerned. The part by E. Winterfeldt deals with various synthetic approaches to camptothecin, an alkaloid of highly interesting properties. Discussion of the synthetic methods includes the important contribution of the author himself to this branch of chemistry. A. Klásek and 0. Weinbergovd present a comprehensive new review on pyrrolizidine alka­loids and their components, the necines and necic acids, dealing with the structure, chemistry, stereochemistry of the com­pounds and with the synthesis and biological effects of the al­kaloids, such as the mutagenic, carcinogenic and antitumour actions. The very readable review by A. Ya. Khorlin and S. E. Zura­­byan gives an up-to-date and well-systematized collection of the methods applicable to the synthesis of glycosaminides, in­cluding the stereospecific and enzymic syntheses, as well as the preparation of S- and N- glycosaminides. The extensive list of references will be of great assistance to chemists working in this field of organic chemistry. AKADÉMIAI KIADÓ Publishing House of the Hungarian Academy of Sciences Budapest Distributors: KULTURA 1389 Budapest P.O.B. 149

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